| Gertrude Stein | KATHY BATES |
| Salvador Dali | ADRIEN BRODY |
| Museum Guide | CARLA BRUNI |
| Adriana | MARION COTILLARD |
| Inez | RACHEL McADAMS |
| Paul | MICHAEL SHEEN |
| Gil | OWEN WILSON |
| Carol | NINA ARIANDA |
| John | KURT FULLER |
| F. Scott Fitzgerald | TOM HIDDLESTON |
| Helen | MIMI KENNEDY |
| Zelda Fitzgerald | ALISON PILL |
| Gabrielle | LÉA SEYDOUX |
| Ernest Hemingway | COREY STOLL |
